A list of NHGRI homepage highlights.
Updated: 23 min 39 sec ago
Communities of skin microbes, such as bacteria, fungi and viruses, remain highly stable in individuals over time, despite exposure to other individuals, clothing and environments, according to new research by NHGRI and NCI scientists. Future studies may help researchers understand how various exposures or disease states alter these skin microbes and, eventually, lead to improved treatments. The study appeared May 5 in Cell.
On Wednesday, May 4, John D. Carpten, Ph.D., a former NHGRI intramural investigator, presented the 12th Jeffrey M. Trent Lecture in Cancer Research at Lipsett Amphitheater, Clinical Center. Dr. Carpten is chair, Department of Translational Genomics and director, Institute of Translational Genomics at the University of Southern California. He is renowned for key discoveries in cancer genetics and genomics. Video of this lecture is now available.
NHGRI researchers have collaborated with physicians and medical geneticists around the world to create the first Atlas of Human Malformation Syndromes in Diverse Populations. Health care providers can use the new atlas to diagnose diverse patients with inherited diseases by comparing physical traits (called phenotypes) and written descriptions of their symptoms with photos and descriptions of people with the same condition and ancestry.
For NHGRI's National DNA Day on April 25, Eric P. Spana, Ph.D. from Duke University presented Harry Potter and the Genetics of Wizarding, the inaugural event for the National DNA Day speaker series. The lecture is now available on NHGRI's YouTube channel, GenomeTV. Dr. Spana is an award-winning instructor in biology who helps students place new information in context with ideas they already find familiar, like Harry Potter, Star Wars and The Avenger.
A major question associated with using genomic medicine in practice is: How should doctors treat patients with disease-associated differences in their genetic code? NHGRI's Clinical Genome Resource (ClinGen), co-funded by NCI, has developed a score-based method to evaluate genomic variants that call for increased clinical focus. The guide will help clinicians decide what medical practices best prevent disease in at-risk patients. The study appears April 28th in Genetics in Medicine.
On April 19-20, NHGRI will host Genomic Medicine IX: Bedside to Bench - Mind the Gaps at the Silver Spring Sheraton, Silver Spring, Maryland. Speakers will focus on moving genomics research from the bedside to the laboratory, and better integrating basic science research with clinically important questions.
A key challenge health care providers face in treating prostate cancer is distinguishing aggressive, potentially life-threatening tumors from curable, less aggressive tumors. NHGRI researchers and their collaborators have identified a specific genomic signature of some aggressive prostate tumors, which may help pinpoint specific treatment options. Findings from the study were published April 14 online in The American Journal of Human Genetics.
In an editorial published April 13th in JAMA Psychiatry, NHGRI Investigator Philip Shaw, M.D., Ph.D., reviews a study that tried to develop growth charts for childhood brain function. Such "neuropsychiatric" charts, though challenging to create, could help health care providers detect when a child's brain function is beginning to go "off-track," and trigger further assessment and intervention.
On April 18th, Gerardo Jimenez-Sanchez, M.D., Ph.D., will present the third lecture in the Genomics and Health Disparities Lecture Series: Genomics in Mexico: Implications for Health Care and the Bioeconomy, at Building 50 on the NIH campus and online at NIH VideoCasting. Dr. Jimenez-Sanchez is an adjunct professor at Harvard T.H. Chan School of Public Health and a founding director for the National Institute of Genomic Medicine (INMEGEN) in Mexico.
Since 2003, NHGRI's ENCyclopedia Of DNA Elements (ENCODE) project has been building a comprehensive parts list of functional elements in the human and mouse genomes. The upcoming workshop - ENCODE 2016: Research Applications and Users Meeting - slated for June 8-10 at Stanford University, offers scientists training, tutorials, new applications and more. For information, registration: