Drosophila melanogaster Genome Project

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Image source: TheAlphaWolf (Own work) [GFDL or CC-BY-3.0], via Wikimedia Commons

About the project

In a collaborative effort with the Berkeley Drosophila Genome Project (BDGP) and Celera Genomics, we have mapped and sequenced the euchromatic portion of the Drosophila melanogaster genome. Release of the drosophila sequence was in 2002 (link). The Drosophila Genome Project was funded by the National Human Genome Research Institute, National Cancer Institute, and Howard Hughes Medical Institute.

Genomic Resources

Access to the Data

Additional Resources

Learn more about Drosophila melanogaster

Related Publications

Wiegmann BM, Richards S. Genomes of Diptera. Curr Opin Insect Sci. 2018 ;25:116-124.

Kaiser TS, Poehn B, Szkiba D, Preussner M, Sedlazeck FJ, Zrim A, et al. The genomic basis of circadian and circalunar timing adaptations in a midge. Nature. 2016 ;540(7631):69-73.

Wang F, Jiang L, Chen Y, Haelterman NA, Bellen HJ, Chen R. FlyVar: a database for genetic variation in Drosophila melanogaster. Database (Oxford). 2015 ;2015.

Fuller ZL, Haynes GD, Zhu D, Batterton M, Chao H, Dugan S, et al. Evidence for stabilizing selection on codon usage in chromosomal rearrangements of Drosophila pseudoobscura. G3 (Bethesda). 2014 ;4(12):2433-49.

Ellis LL, Huang W, Quinn AM, Ahuja A, Alfrejd B, Gomez FE, et al. Intrapopulation genome size variation in D. melanogaster reflects life history variation and plasticity. PLoS Genet. 2014 ;10(7):e1004522.

Chen Z-X, Sturgill D, Qu J, Jiang H, Park S, Boley N, et al. Comparative validation of the D. melanogaster modENCODE transcriptome annotation. Genome Res. 2014 ;24(7):1209-23.

Huang W, Massouras A, Inoue Y, Peiffer J, Ràmia M, Tarone AM, et al.. Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines. Genome Res. 2014 ;24(7):1193-208.

Jusiak B, Karandikar UC, Kwak S-J, Wang F, Wang H, Chen R, et al. Regulation of Drosophila eye development by the transcription factor Sine oculis. PLoS One. 2014 ;9(2):e89695.

English AC, Richards S, Han Y, Wang M, Vee V, Qu J, et al. Mind the gap: upgrading genomes with Pacific Biosciences RS long-read sequencing technology. PLoS One. 2012 ;7(11):e47768.