Drosophila melanogaster Genome Project

Image source: TheAlphaWolf (Own work) [GFDL or CC-BY-3.0], via Wikimedia Commons

About the project

In a collaborative effort with the Berkeley Drosophila Genome Project (BDGP) and Celera Genomics, we have mapped and sequenced the euchromatic portion of the Drosophila melanogaster genome. Release of the drosophila sequence was in 2002 (link). The Drosophila Genome Project was funded by the National Human Genome Research Institute, National Cancer Institute, and Howard Hughes Medical Institute.

Genomic Resources

Access to the Data

Additional Resources

Learn more about Drosophila melanogaster

Related Publications

Huang W, Richards S, Carbone MAnna, Zhu D, Anholt RRH, Ayroles JF, et al. Epistasis dominates the genetic architecture of Drosophila quantitative traits. Proc Natl Acad Sci U S A. 2012 ;109(39):15553-9.

Ober U, Ayroles JF, Stone EA, Richards S, Zhu D, Gibbs RA, et al. Using whole-genome sequence data to predict quantitative trait phenotypes in Drosophila melanogaster. PLoS Genet. 2012 ;8(5):e1002685.

Mackay TFC, Richards S, Stone EA, Barbadilla A, Ayroles JF, Zhu D, et al. The Drosophila melanogaster Genetic Reference Panel. Nature. 2012 ;482(7384):173-8.

Daines B, Wang H, Wang L, Li Y, Han Y, Emmert D, et al. The Drosophila melanogaster transcriptome by paired-end RNA sequencing. Genome Res. 2011 ;21(2):315-24.

Wang H, Chattopadhyay A, Li Z, Daines B, Li Y, Gao C, et al. Rapid identification of heterozygous mutations in Drosophila melanogaster using genomic capture sequencing. Genome Res. 2010 ;20(7):981-8.

Ostrin EJ, Li Y, Hoffman K, Liu J, Wang K, Zhang L, et al. Genome-wide identification of direct targets of the Drosophila retinal determination protein Eyeless. Genome Res. 2006 ;16(4):466-76.

Siepel A, Bejerano G, Pedersen JS, Hinrichs AS, Hou M, Rosenbloom K, et al. Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes. Genome Res. 2005 ;15(8):1034-50.

Richards S, Liu Y, Bettencourt BR, Hradecky P, Letovsky S, Nielsen R, et al. Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution. Genome Res. 2005 ;15(1):1-18.

Jin P, Zarnescu DC, Ceman S, Nakamoto M, Mowrey J, Jongens TA, et al. Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway. Nat Neurosci. 2004 ;7(2):113-7.

Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, et al. Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence. Genome Biol. 2002 ;3(12):RESEARCH0079.