The 1000 Genomes Project: data management and community access.

TitleThe 1000 Genomes Project: data management and community access.
Publication TypeJournal Article
Year of Publication2012
AuthorsClarke, L, Zheng-Bradley, X, Smith, R, Kulesha, E, Xiao, C, Toneva, I, Vaughan, B, Preuss, D, Leinonen, R, Shumway, M, Sherry, S, Flicek, P
Corporate Authors
JournalNat Methods
Volume9
Issue5
Pagination459-62
Date Published2012 Apr 27
ISSN1548-7105
KeywordsComputational Biology, Databases, Genetic, Genetic Variation, Genome, Human, Genomics, Humans, Sequence Analysis, DNA
Abstract

The 1000 Genomes Project was launched as one of the largest distributed data collection and analysis projects ever undertaken in biology. In addition to the primary scientific goals of creating both a deep catalog of human genetic variation and extensive methods to accurately discover and characterize variation using new sequencing technologies, the project makes all of its data publicly available. Members of the project data coordination center have developed and deployed several tools to enable widespread data access.

DOI10.1038/nmeth.1974
Alternate JournalNat. Methods
PubMed ID22543379
PubMed Central IDPMC3340611
Grant ListU54 HG003067 / HG / NHGRI NIH HHS / United States
G1000758 / / Medical Research Council / United Kingdom
U01 HG006513 / HG / NHGRI NIH HHS / United States
U54 HG003273 / HG / NHGRI NIH HHS / United States
P20 MD006899 / MD / NIMHD NIH HHS / United States
090532 / / Wellcome Trust / United Kingdom
095908 / / Wellcome Trust / United Kingdom
P01 CA101937 / CA / NCI NIH HHS / United States
085532 / / Wellcome Trust / United Kingdom
Z99 LM999999 / NU / Intramural NIH HHS / United States