Adding resolution and dimensionality to comparative genomics: moving from reference genomes to clade genomics.

TitleAdding resolution and dimensionality to comparative genomics: moving from reference genomes to clade genomics.
Publication TypeJournal Article
Year of Publication2018
AuthorsRogers, J
JournalGenome Biol
Volume19
Issue1
Pagination115
Date Published2018 Aug 14
ISSN1474-760X
KeywordsAnimals, Computational Biology, Genome, Genomics, Humans, Phylogeny, Reference Standards, Sequence Analysis, DNA
Abstract

The main goal and promise of comparative genomics has been to create a comprehensive catalog of genomic information and function across the phenomenal diversity of living systems. A recent study has demonstrated the evolutionary insights possible by generating high-quality whole-genome assemblies from multiple species of a clade.
DOI10.1186/s13059-018-1500-7
Alternate JournalGenome Biol
PubMed ID30107805
PubMed Central IDPMC6090731
Grant ListR01-EY026045 / NH / NIH HHS / United States
R24-OD11173 / NH / NIH HHS / United States
P51-OD011106 / NH / NIH HHS / United States

Similar Publications

Malamon JS, Farrell JJ, Xia LCharlie, Dombroski BA, Das RG, Way J, et al.. A comparative study of structural variant calling in WGS from Alzheimer's disease families. Life Sci Alliance. 2024;7(5).
Hu J, Korchina V, Zouk H, Harden MV, Murdock D, Macbeth A, et al.. Genetic sex validation for sample tracking in next-generation sequencing clinical testing. BMC Res Notes. 2024;17(1):62.
Wang Q, Clark KM, Tiwari R, Raju N, Tharp GK, Rogers J, et al.. The CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression. Cell. 2024;187(5):1223-1237.e16.