A baboon (Papio hamadryas) with an isochromosome for the long arm of the X.

TitleA baboon (Papio hamadryas) with an isochromosome for the long arm of the X.
Publication TypeJournal Article
Year of Publication1998
AuthorsMoore, CM, Leland, MM, Brzyski, RG, McKeand, J, Witte, SM, Rogers, J
JournalCytogenet Cell Genet
Volume82
Issue1-2
Pagination80-2
Date Published1998
ISSN0301-0171
KeywordsAnimals, Estrus, Female, Infertility, Female, Karyotyping, Metacarpus, Papio, Radiography, Sex Chromosome Aberrations, X Chromosome
Abstract

A 5.5-yr-old female baboon was evaluated for sexual immaturity. She was small for her age and had normal external female genitalia. However, she lacked cyclical perineal turgescence and displayed atypical coloration of the perineal skin. Laparoscopy revealed a small uterus and absence of both ovaries. Cytogenetic analysis revealed a 42,X,i(X)(q10) karyotype. DNA analysis using loci DXS1683, which maps to Xp22.1, and DXS297, which maps to Xq27.3, was consistent with inheritance of the normal X chromosome from the dam and formation of the isochromosome Xq from the paternal X.

DOI10.1159/000015069
Alternate JournalCytogenet. Cell Genet.
PubMed ID9763665