Community annotation: procedures, protocols, and supporting tools.

TitleCommunity annotation: procedures, protocols, and supporting tools.
Publication TypeJournal Article
Year of Publication2006
AuthorsElsik, CG, Worley, KC, Zhang, L, Milshina, NV, Jiang, H, Reese, JT, Childs, KL, Venkatraman, A, C Dickens, M, Weinstock, GM, Gibbs, RA
JournalGenome Res
Volume16
Issue11
Pagination1329-33
Date Published2006 Nov
ISSN1088-9051
KeywordsAnimals, Bees, Databases, Genetic, Genome, Human, Genomics, Humans, Models, Genetic, Molecular Sequence Data, Sequence Analysis
Abstract

Investigators at the Baylor College of Medicine Human Genome Sequencing Center (BCM-HGSC) and BeeBase organized a community-wide effort to manually annotate the honey bee (Apis mellifera) genome. Although various strategies for manual annotation have been used in the past, the value of dispersed community annotation has not yet been demonstrated. Here we make a case for the merit of dispersed community annotation. We present annotation procedures, standard protocols, and tools used for sequence analysis, data submission, and data management. We also report lessons learned from this dispersed community annotation effort for a metazoan genome.

DOI10.1101/gr.5580606
Alternate JournalGenome Res.
PubMed ID17065605
Grant ListU54 HG003273 / HG / NHGRI NIH HHS / United States
P-P41-HG000739-13 / HG / NHGRI NIH HHS / United States