Community annotation: procedures, protocols, and supporting tools.

TitleCommunity annotation: procedures, protocols, and supporting tools.
Publication TypeJournal Article
Year of Publication2006
AuthorsElsik, CG, Worley, KC, Zhang, L, Milshina, NV, Jiang, H, Reese, JT, Childs, KL, Venkatraman, A, C Dickens, M, Weinstock, GM, Gibbs, RA
JournalGenome Res
Date Published2006 Nov
KeywordsAnimals, Bees, Databases, Genetic, Genome, Human, Genomics, Humans, Models, Genetic, Molecular Sequence Data, Sequence Analysis

Investigators at the Baylor College of Medicine Human Genome Sequencing Center (BCM-HGSC) and BeeBase organized a community-wide effort to manually annotate the honey bee (Apis mellifera) genome. Although various strategies for manual annotation have been used in the past, the value of dispersed community annotation has not yet been demonstrated. Here we make a case for the merit of dispersed community annotation. We present annotation procedures, standard protocols, and tools used for sequence analysis, data submission, and data management. We also report lessons learned from this dispersed community annotation effort for a metazoan genome.

Alternate JournalGenome Res
PubMed ID17065605
Grant ListP-P41-HG000739-13 / HG / NHGRI NIH HHS / United States

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