DATA RESOURCES AND ANALYSES FAIR Header Reference genome: A TRUSTworthy standard.

TitleDATA RESOURCES AND ANALYSES FAIR Header Reference genome: A TRUSTworthy standard.
Publication TypeJournal Article
Year of Publication2023
AuthorsWright, A, Wilkinson, MD, Mungall, C, Cain, S, Richards, S, Sternberg, P, Provin, E, Jacobs, JL, Geib, S, Raciti, D, Yook, K, Stein, L, Molik, DC
JournalbioRxiv
Date Published2023 Dec 20
ISSN2692-8205
Abstract

The lack of interoperable data standards among reference genome data-sharing platforms inhibits cross-platform analysis while increasing the risk of data provenance loss. Here, we describe the FAIR-bioHeaders Reference genome (FHR), a metadata standard guided by the principles of Findability, Accessibility, Interoperability, and Reuse (FAIR) in addition to the principles of Transparency, Responsibility, User focus, Sustainability, and Technology (TRUST). The objective of FHR is to provide an extensive set of data serialisation methods and minimum data field requirements while still maintaining extensibility, flexibility, and expressivity in an increasingly decentralised genomic data ecosystem. The effort needed to implement FHR is low; FHR's design philosophy ensures easy implementation while retaining the benefits gained from recording both machine and human-readable provenance.

DOI10.1101/2023.11.29.569306
Alternate JournalbioRxiv
PubMed ID38076838
PubMed Central IDPMC10705436
Grant ListU24 HG002223 / HG / NHGRI NIH HHS / United States