Title | DATA RESOURCES AND ANALYSES FAIR Header Reference genome: A TRUSTworthy standard. |
Publication Type | Journal Article |
Year of Publication | 2023 |
Authors | Wright, A, Wilkinson, MD, Mungall, C, Cain, S, Richards, S, Sternberg, P, Provin, E, Jacobs, JL, Geib, S, Raciti, D, Yook, K, Stein, L, Molik, DC |
Journal | bioRxiv |
Date Published | 2023 Dec 20 |
ISSN | 2692-8205 |
Abstract | The lack of interoperable data standards among reference genome data-sharing platforms inhibits cross-platform analysis while increasing the risk of data provenance loss. Here, we describe the FAIR-bioHeaders Reference genome (FHR), a metadata standard guided by the principles of Findability, Accessibility, Interoperability, and Reuse (FAIR) in addition to the principles of Transparency, Responsibility, User focus, Sustainability, and Technology (TRUST). The objective of FHR is to provide an extensive set of data serialisation methods and minimum data field requirements while still maintaining extensibility, flexibility, and expressivity in an increasingly decentralised genomic data ecosystem. The effort needed to implement FHR is low; FHR's design philosophy ensures easy implementation while retaining the benefits gained from recording both machine and human-readable provenance. |
DOI | 10.1101/2023.11.29.569306 |
Alternate Journal | bioRxiv |
PubMed ID | 38076838 |
PubMed Central ID | PMC10705436 |
Grant List | U24 HG002223 / HG / NHGRI NIH HHS / United States |