%0 Journal Article %J Sci Adv %D 2019 %T The comparative genomics and complex population history of baboons. %A Jeffrey Rogers %A Raveendran, Muthuswamy %A R. Alan Harris %A Mailund, Thomas %A Leppälä, Kalle %A Athanasiadis, Georgios %A Schierup, Mikkel Heide %A Cheng, Jade %A Munch, Kasper %A Walker, Jerilyn A %A Konkel, Miriam K %A Jordan, Vallmer %A Steely, Cody J %A Beckstrom, Thomas O %A Bergey, Christina %A Burrell, Andrew %A Schrempf, Dominik %A Noll, Angela %A Kothe, Maximillian %A Kopp, Gisela H %A Liu, Yue %A Murali, Shwetha %A Billis, Konstantinos %A Martin, Fergal J %A Muffato, Matthieu %A Cox, Laura %A Else, James %A Disotell, Todd %A Donna M Muzny %A Phillips-Conroy, Jane %A Aken, Bronwen %A Eichler, Evan E %A Marques-Bonet, Tomas %A Kosiol, Carolin %A Batzer, Mark A %A Hahn, Matthew W %A Tung, Jenny %A Zinner, Dietmar %A Roos, Christian %A Jolly, Clifford J %A Richard A Gibbs %A Kim C Worley %K Animals %K Base Sequence %K Biological Evolution %K Female %K Gene Flow %K Genomics %K Haplotypes %K Humans %K Hybridization, Genetic %K Male %K Papio %K Phylogeny %K Polymorphism, Genetic %K Whole Genome Sequencing %X

Recent studies suggest that closely related species can accumulate substantial genetic and phenotypic differences despite ongoing gene flow, thus challenging traditional ideas regarding the genetics of speciation. Baboons (genus ) are Old World monkeys consisting of six readily distinguishable species. Baboon species hybridize in the wild, and prior data imply a complex history of differentiation and introgression. We produced a reference genome assembly for the olive baboon () and whole-genome sequence data for all six extant species. We document multiple episodes of admixture and introgression during the radiation of baboons, thus demonstrating their value as a model of complex evolutionary divergence, hybridization, and reticulation. These results help inform our understanding of similar cases, including modern humans, Neanderthals, Denisovans, and other ancient hominins.

%B Sci Adv %V 5 %P eaau6947 %8 2019 Jan %G eng %N 1 %1 https://www.ncbi.nlm.nih.gov/pubmed/30854422?dopt=Abstract %R 10.1126/sciadv.aau6947