The genome of the model beetle and pest Tribolium castaneum.

TitleThe genome of the model beetle and pest Tribolium castaneum.
Publication TypeJournal Article
Year of Publication2008
AuthorsRichards, S, Gibbs, RA, Weinstock, GM, Brown, SJ, Denell, R, Beeman, RW, Gibbs, RA, Beeman, RW, Brown, SJ, Bucher, G, Friedrich, M, Grimmelikhuijzen, CJP, Klingler, M, Lorenzen, M, Richards, S, Roth, S, Schröder, R, Tautz, D, Zdobnov, EM, Muzny, D, Gibbs, RA, Weinstock, GM, Attaway, T, Bell, S, Buhay, CJ, Chandrabose, MN, Chavez, D, Clerk-Blankenburg, KP, Cree, A, Dao, M, Davis, C, Chacko, J, Dinh, H, Dugan-Rocha, S, Fowler, G, Garner, TT, Garnes, J, Gnirke, A, Hawes, A, Hernandez, J, Hines, S, Holder, M, Hume, J, Jhangiani, SN, Joshi, V, Khan, ZMohid, Jackson, L, Kovar, C, Kowis, A, Lee, S, Lewis, LR, Margolis, J, Morgan, M, Nazareth, LV, Nguyen, N, Okwuonu, G, Parker, D, Richards, S, Ruiz, S-J, Santibanez, J, Savard, J, Scherer, SE, Schneider, B, Sodergren, E, Tautz, D, Vattahil, S, Villasana, D, White, CS, Wright, R, Park, Y, Beeman, RW, Lord, J, Oppert, B, Lorenzen, M, Brown, S, Wang, L, Savard, J, Tautz, D, Richards, S, Weinstock, G, Gibbs, RA, Liu, Y, Worley, KC, Weinstock, G, Elsik, CG, Reese, JT, Elhaik, E, Landan, G, Graur, D, Arensburger, P, Atkinson, P, Beeman, RW, Beidler, J, Brown, SJ, Demuth, JP, Drury, DW, Du, Y-Z, Fujiwara, H, Lorenzen, M, Maselli, V, Osanai, M, Park, Y, Robertson, HM, Tu, Z, Wang, J-jun, Wang, S, Richards, S, Song, H, Zhang, L, Sodergren, E, Werner, D, Stanke, M, Morgenstern, B, Solovyev, V, Kosarev, P, Brown, G, Chen, H-C, Ermolaeva, O, Hlavina, W, Kapustin, Y, Kiryutin, B, Kitts, P, Maglott, D, Pruitt, K, Sapojnikov, V, Souvorov, A, Mackey, AJ, Waterhouse, RM, Wyder, S, Zdobnov, EM, Zdobnov, EM, Wyder, S, Kriventseva, EV, Kadowaki, T, Bork, P, Aranda, M, Bao, R, Beermann, A, Berns, N, Bolognesi, R, Bonneton, F, Bopp, D, Brown, SJ, Bucher, G, Butts, T, Chaumot, A, Denell, RE, Ferrier, DEK, Friedrich, M, Gordon, CM, Jindra, M, Klingler, M, Lan, Q, H Lattorff, MG, Laudet, V, von Levetsow, C, Liu, Z, Lutz, R, Lynch, JA, da Fonseca, RNunes, Posnien, N, Reuter, R, Roth, S, Savard, J, Schinko, JB, Schmitt, C, Schoppmeier, M, Schröder, R, Shippy, TD, Simonnet, F, Marques-Souza, H, Tautz, D, Tomoyasu, Y, Trauner, J, Van der Zee, M, Vervoort, M, Wittkopp, N, Wimmer, EA, Yang, X, Jones, AK, Sattelle, DB, Ebert, PR, Nelson, D, Scott, JG, Beeman, RW, Muthukrishnan, S, Kramer, KJ, Arakane, Y, Beeman, RW, Zhu, Q, Hogenkamp, D, Dixit, R, Oppert, B, Jiang, H, Zou, Z, Marshall, J, Elpidina, E, Vinokurov, K, Oppert, C, Zou, Z, Evans, J, Lu, Z, Zhao, P, Sumathipala, N, Altincicek, B, Vilcinskas, A, Williams, M, Hultmark, D, Hetru, C, Jiang, H, Grimmelikhuijzen, CJP, Hauser, F, Cazzamali, G, Williamson, M, Park, Y, Li, B, Tanaka, Y, Predel, R, Neupert, S, Schachtner, J, Verleyen, P, Raible, F, Bork, P, Friedrich, M, Walden, KKO, Robertson, HM, Angeli, S, Forêt, S, Bucher, G, Schuetz, S, Maleszka, R, Wimmer, EA, Beeman, RW, Lorenzen, M, Tomoyasu, Y, Miller, SC, Grossmann, D, Bucher, G
Corporate AuthorsTribolium Genome Sequencing Consortium
JournalNature
Volume452
Issue7190
Pagination949-55
Date Published2008 Apr 24
ISSN1476-4687
KeywordsAnimals, Base Composition, Body Patterning, Cytochrome P-450 Enzyme System, DNA Transposable Elements, Genes, Insect, Genome, Insect, Growth and Development, Humans, Insecticides, Neurotransmitter Agents, Oogenesis, Phylogeny, Proteome, Receptors, G-Protein-Coupled, Receptors, Odorant, Repetitive Sequences, Nucleic Acid, RNA Interference, Taste, Telomere, Tribolium, Vision, Ocular
Abstract

Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agricultural products. We describe its genome sequence here. This omnivorous beetle has evolved the ability to interact with a diverse chemical environment, as shown by large expansions in odorant and gustatory receptors, as well as P450 and other detoxification enzymes. Development in Tribolium is more representative of other insects than is Drosophila, a fact reflected in gene content and function. For example, Tribolium has retained more ancestral genes involved in cell-cell communication than Drosophila, some being expressed in the growth zone crucial for axial elongation in short-germ development. Systemic RNA interference in T. castaneum functions differently from that in Caenorhabditis elegans, but nevertheless offers similar power for the elucidation of gene function and identification of targets for selective insect control.

DOI10.1038/nature06784
Alternate JournalNature
PubMed ID18362917
Grant ListU54 HG003273 / HG / NHGRI NIH HHS / United States
R01 HD029594-16 / HD / NICHD NIH HHS / United States
/ / Intramural NIH HHS / United States
R01 HD029594 / HD / NICHD NIH HHS / United States
BBS/B/12067/2 / / Biotechnology and Biological Sciences Research Council / United Kingdom
BBS/B/12067 / / Biotechnology and Biological Sciences Research Council / United Kingdom
R01 GM058634 / GM / NIGMS NIH HHS / United States