Integrating ethics and science in the International HapMap Project.

TitleIntegrating ethics and science in the International HapMap Project.
Publication TypeJournal Article
Year of Publication2004
Corporate AuthorsInternational HapMap Consortium
JournalNat Rev Genet
Date Published2004 Jun
KeywordsDatabases, Genetic, Genetic Privacy, Genetic Variation, Genome, Human, Genomics, Haplotypes, Humans, Informed Consent, International Cooperation, Population Groups, Sampling Studies

Genomics resources that use samples from identified populations raise scientific, social and ethical issues that are, in many ways, inextricably linked. Scientific decisions about which populations to sample to produce the HapMap, an international genetic variation resource, have raised questions about the relationships between the social identities used to recruit participants and the biological findings of studies that will use the HapMap. The sometimes problematic implications of those complex relationships have led to questions about how to conduct genetic variation research that uses identified populations in an ethical way, including how to involve members of a population in evaluating the risks and benefits posed for everyone who shares that identity. The ways in which these issues are linked is increasingly drawing the scientific and ethical spheres of genomics research closer together.

Alternate JournalNat Rev Genet
PubMed ID15153999
PubMed Central IDPMC2271136
Grant List / / Wellcome Trust / United Kingdom
R01 HG002189-01 / HG / NHGRI NIH HHS / United States
R01 HG002189-02 / HG / NHGRI NIH HHS / United States
R01 HG002189-03 / HG / NHGRI NIH HHS / United States

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