An Introduction to the Callithrix Genus and Overview of Recent Advances in Marmoset Research.

TitleAn Introduction to the Callithrix Genus and Overview of Recent Advances in Marmoset Research.
Publication TypeJournal Article
Year of Publication2020
AuthorsMalukiewicz, J, Boere, V, de Oliveira, MAdélia Bo, D'arc, M, Ferreira, JVA, French, J, Housman, G, de Souza, CIgayara, Jerusalinsky, L, de Melo, FR, Valença-Montenegro, MM, Moreira, SBahadian, Silva, Ide Oliveir, Pacheco, FSantos, Rogers, J, Pissinatti, A, Del Rosario, RCH, Ross, C, Ruiz-Miranda, CR, Pereira, LCM, Schiel, N, da Silva, Fde Fátima, Souto, A, Šlipogor, V, Tardif, S
JournalILAR J
Date Published2020 Dec 31
KeywordsAnimals, Brazil, Callithrix, Genomics, Hybridization, Genetic, Yellow Fever, Zika Virus, Zika Virus Infection

We provide here a current overview of marmoset (Callithrix) evolution, hybridization, species biology, basic/biomedical research, and conservation initiatives. Composed of 2 subgroups, the aurita group (C aurita and C flaviceps) and the jacchus group (C geoffroyi, C jacchus, C kuhlii, and C penicillata), this relatively young primate radiation is endemic to the Brazilian Cerrado, Caatinga, and Atlantic Forest biomes. Significant impacts on Callithrix within these biomes resulting from anthropogenic activity include (1) population declines, particularly for the aurita group; (2) widespread geographic displacement, biological invasions, and range expansions of C jacchus and C penicillata; (3) anthropogenic hybridization; and (4) epizootic Yellow Fever and Zika viral outbreaks. A number of Brazilian legal and conservation initiatives are now in place to protect the threatened aurita group and increase research about them. Due to their small size and rapid life history, marmosets are prized biomedical models. As a result, there are increasingly sophisticated genomic Callithrix resources available and burgeoning marmoset functional, immuno-, and epigenomic research. In both the laboratory and the wild, marmosets have given us insight into cognition, social group dynamics, human disease, and pregnancy. Callithrix jacchus and C penicillata are emerging neotropical primate models for arbovirus disease, including Dengue and Zika. Wild marmoset populations are helping us understand sylvatic transmission and human spillover of Zika and Yellow Fever viruses. All of these factors are positioning marmosets as preeminent models to facilitate understanding of facets of evolution, hybridization, conservation, human disease, and emerging infectious diseases.

Alternate JournalILAR J
PubMed ID34933341
Grant List302044/2014-0 / / Brazilian CNPq Jovens Talentos Postdoctoral Fellowship /
300264/2018-6 / / American Society of Primatologists Conservation Small Grant /

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