Reorganization and expansion of the nidoviral family Arteriviridae.

 
TitleReorganization and expansion of the nidoviral family Arteriviridae.
Publication TypeJournal Article
Year of Publication2016
AuthorsKuhn, JH, Lauck, M, Bailey, AL, Shchetinin, AM, Vishnevskaya, TV, Bào, Y, Ng, TFei Fan, LeBreton, M, Schneider, BS, Gillis, A, Tamoufe, U, Diffo, JLe Doux, Takuo, JMichel, Kondov, NO, Coffey, LL, Wolfe, ND, Delwart, E, Clawson, AN, Postnikova, E, Bollinger, L, Lackemeyer, MG, Radoshitzky, SR, Palacios, G, Wada, J, Shevtsova, ZV, Jahrling, PB, Lapin, BA, Deriabin, PG, Dunowska, M, Alkhovsky, SV, Rogers, J, Friedrich, TC, O'Connor, DH, Goldberg, TL
JournalArch Virol
Volume161
Issue3
Pagination755-68
Date Published2016 Mar
ISSN1432-8798
KeywordsArteriviridae, Cluster Analysis, Genome, Viral, Open Reading Frames, Phylogeny, RNA Virus Infections, RNA, Viral, Sequence Homology, Terminology as Topic
Abstract

The family Arteriviridae presently includes a single genus Arterivirus. This genus includes four species as the taxonomic homes for equine arteritis virus (EAV), lactate dehydrogenase-elevating virus (LDV), porcine respiratory and reproductive syndrome virus (PRRSV), and simian hemorrhagic fever virus (SHFV), respectively. A revision of this classification is urgently needed to accommodate the recent description of eleven highly divergent simian arteriviruses in diverse African nonhuman primates, one novel arterivirus in an African forest giant pouched rat, and a novel arterivirus in common brushtails in New Zealand. In addition, the current arterivirus nomenclature is not in accordance with the most recent version of the International Code of Virus Classification and Nomenclature. Here we outline an updated, amended, and improved arterivirus taxonomy based on current data. Taxon-specific sequence cut-offs are established relying on a newly established open reading frame 1b phylogeny and pairwise sequence comparison (PASC) of coding-complete arterivirus genomes. As a result, the current genus Arterivirus is replaced by five genera: Equartevirus (for EAV), Rodartevirus (LDV + PRRSV), Simartevirus (SHFV + simian arteriviruses), Nesartevirus (for the arterivirus from forest giant pouched rats), and Dipartevirus (common brushtail arterivirus). The current species Porcine reproductive and respiratory syndrome virus is divided into two species to accommodate the clear divergence of the European and American "types" of PRRSV, both of which now receive virus status. The current species Simian hemorrhagic fever virus is divided into nine species to accommodate the twelve known simian arteriviruses. Non-Latinized binomial species names are introduced to replace all current species names to clearly differentiate them from virus names, which remain largely unchanged.

DOI10.1007/s00705-015-2672-z
Alternate JournalArch. Virol.
PubMed ID26608064
Grant ListT32 GM008692 / GM / NIGMS NIH HHS / United States
TW009237 / TW / FIC NIH HHS / United States
/ / Intramural NIH HHS / United States
HHSN272200700016I / / PHS HHS / United States
R01 AI077376 / AI / NIAID NIH HHS / United States
P51OD011106 / OD / NIH HHS / United States