The role of drinking water sources, consumption of vegetables and seafood in relation to blood arsenic concentrations of Jamaican children with and without Autism Spectrum Disorders.

 
TitleThe role of drinking water sources, consumption of vegetables and seafood in relation to blood arsenic concentrations of Jamaican children with and without Autism Spectrum Disorders.
Publication TypeJournal Article
Year of Publication2012
AuthorsRahbar, MH, Samms-Vaughan, M, Ardjomand-Hessabi, M, Loveland, KA, Dickerson, AS, Chen, Z, Bressler, J, Shakespeare-Pellington, S, Grove, ML, Bloom, K, Wirth, J, Pearson, DA, Boerwinkle, E
JournalSci Total Environ
Volume433
Pagination362-70
Date Published2012 Sep 1
ISSN1879-1026
KeywordsArsenic, Case-Control Studies, Child, Child Development Disorders, Pervasive, Drinking Water, Humans, Jamaica, Seafood, Vegetables
Abstract

Arsenic is a toxic metal with harmful effects on human health, particularly on cognitive function. Autism Spectrum Disorders (ASDs) are lifelong neurodevelopmental and behavioral disorders manifesting in infancy or early childhood. We used data from 130 children between 2 and 8 years (65 pairs of ASD cases with age- and sex-matched control), to compare the mean total blood arsenic concentrations in children with and without ASDs in Kingston, Jamaica. Based on univariable analysis, we observed a significant difference between ASD cases and controls (4.03 μg/L for cases vs. 4.48 μg/L for controls, P

DOI10.1016/j.scitotenv.2012.06.085
Alternate JournalSci. Total Environ.
PubMed ID22819887
PubMed Central IDPMC3418487
Grant ListR01 ES022165 / ES / NIEHS NIH HHS / United States
R21 HD057808 / HD / NICHD NIH HHS / United States
R21HD057808 / HD / NICHD NIH HHS / United States
UL1 RR024148 / RR / NCRR NIH HHS / United States
UL1 RR024148 / RR / NCRR NIH HHS / United States