A simple and evolutional approach proven to recanalise the nasolacrimal duct obstruction.

TitleA simple and evolutional approach proven to recanalise the nasolacrimal duct obstruction.
Publication TypeJournal Article
Year of Publication2009
AuthorsChen, D, Ge, J, Wang, L, Gao, Q, Ma, P, Li, N, Li, D-Q, Wang, Z
JournalBr J Ophthalmol
Date Published2009 Nov
KeywordsAnimals, Catheterization, Dacryocystorhinostomy, Equipment Design, Female, Humans, Lacrimal Duct Obstruction, Macaca mulatta, Male, Middle Aged, Nasolacrimal Duct, Postoperative Care, Wound Healing

AIM: To evaluate a new approach of recanalisation of nasolacrimal duct obstruction (RC-NLDO) in the treatment of the nasolacrimal duct obstruction (NLDO) and chronic dacryocystitis.METHODS: 583 patients with 641 eyes suffering from NLDO and chronic dacryocystitis were enrolled in this study. The RC-NLDO was performed in 506 eyes, with 135 eyes undergoing external dacryocystorhinostomy (EX-DCR) as controls. Patient follow-up for 54 months was evaluated by symptoms, dye disappearance test, lacrimal irrigation and digital subtraction dacryocystogram. The RC-NLDO was also performed in 12 rhesus monkeys for histopathological examination.RESULTS: The clinical success rates were 93.1% in 506 cases of RC-NLDO and 91.11% in 135 cases of EX-DCR. The success rates for second surgery were achieved in 85.19% on RC-NLDO and 40.0% on EX-DCR. No major intra- or postoperative complications were observed in the RC-NLDO group. The mean operative duration was 12.5 min for RC-NLDO and 40.3 min for EX-DCR (p<0.001). A pathological study in rhesus monkeys demonstrated that the RC-NLDO wounded epithelium in nasolacrimal duct healed completely within 1 month without granulation tissue formation.CONCLUSION: The findings demonstrate that the RC-NLDO is a simple and effective approach proven to recanalise the obstructed nasolacrimal duct with a comparable success rate to EX-DCR.

Alternate JournalBr J Ophthalmol
PubMed ID19416937
PubMed Central IDPMC2760725

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