Transcriptome of Treponema pallidum: gene expression profile during experimental rabbit infection.

TitleTranscriptome of Treponema pallidum: gene expression profile during experimental rabbit infection.
Publication TypeJournal Article
Year of Publication2005
AuthorsSmajs, D, McKevitt, M, Howell, JK, Norris, SJ, Cai, W-W, Palzkill, T, Weinstock, GM
JournalJ Bacteriol
Volume187
Issue5
Pagination1866-74
Date Published2005 Mar
ISSN0021-9193
KeywordsAnimals, Gene Expression, Gene Expression Profiling, Oligonucleotide Array Sequence Analysis, Open Reading Frames, Rabbits, RNA, Bacterial, RNA, Messenger, Syphilis, Treponema pallidum
Abstract

RNA transcript levels in the syphilis spirochete Treponema pallidum subsp. pallidum (Nichols) isolated from experimentally infected rabbits were determined by the use of DNA microarray technology. This characterization of the T. pallidum transcriptome during experimental infection provides further insight into the importance of gene expression levels for the survival and pathogenesis of this bacterium.

DOI10.1128/JB.187.5.1866-1874.2005
Alternate JournalJ. Bacteriol.
PubMed ID15716460
PubMed Central IDPMC1063989
Grant ListR01 AI045842 / AI / NIAID NIH HHS / United States
R01 DA013759 / DA / NIDA NIH HHS / United States
AI45842 / AI / NIAID NIH HHS / United States
R01 AI049252 / AI / NIAID NIH HHS / United States
R01 AI49252 / AI / NIAID NIH HHS / United States
R01 DE12488 / DE / NIDCR NIH HHS / United States
R01 DE13759 / DE / NIDCR NIH HHS / United States
R01 EY013759 / EY / NEI NIH HHS / United States