Whole Transcriptome Sequencing Analyses Reveal Molecular Markers of Blood Pressure Response to Thiazide Diuretics.

TitleWhole Transcriptome Sequencing Analyses Reveal Molecular Markers of Blood Pressure Response to Thiazide Diuretics.
Publication TypeJournal Article
Year of Publication2017
AuthorsSá, ACaroline C, Webb, A, Gong, Y, McDonough, CW, Datta, S, Langaee, TY, Turner, ST, Beitelshees, AL, Chapman, AB, Boerwinkle, E, Gums, JG, Scherer, SE, Cooper-Dehoff, RM, Sadee, W, Johnson, JA
JournalSci Rep
Volume7
Issue1
Pagination16068
Date Published2017 11 22
ISSN2045-2322
KeywordsAlleles, Biomarkers, Blood Pressure, CCAAT-Enhancer-Binding Protein-delta, Chlorthalidone, Diuretics, Female, Gene Expression Profiling, Gene Expression Regulation, Humans, Hydrochlorothiazide, Logistic Models, Male, Middle Aged, Potassium, Reproducibility of Results, RNA, Messenger, ROC Curve, Transcription Factors, Uric Acid
Abstract

Thiazide diuretics (TD) are commonly prescribed anti-hypertensives worldwide. However,

DOI10.1038/s41598-017-16343-z
Alternate JournalSci Rep
PubMed ID29167564
PubMed Central IDPMC5700078
Grant ListU19 GM061388 / GM / NIGMS NIH HHS / United States
UL1 TR000064 / TR / NCATS NIH HHS / United States
U01 GM074492 / GM / NIGMS NIH HHS / United States
UL1 TR001427 / TR / NCATS NIH HHS / United States
UL1 TR000135 / TR / NCATS NIH HHS / United States
UL1 TR000454 / TR / NCATS NIH HHS / United States
U19 GM061390 / GM / NIGMS NIH HHS / United States

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