Publications
Direct regulation of GTP homeostasis by (p)ppGpp: a critical component of viability and stress resistance. Mol Cell. 2012 ;48(2):231-41.
. The Drosophila melanogaster Genetic Reference Panel. Nature. 2012 ;482(7384):173-8.
. Epistasis dominates the genetic architecture of Drosophila quantitative traits. Proc Natl Acad Sci U S A. 2012 ;109(39):15553-9.
. Evaluation of 16S rDNA-based community profiling for human microbiome research. PLoS One. 2012 ;7(6):e39315.
Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling. Cell. 2012 ;150(3):533-48.
. A framework for human microbiome research. Nature. 2012 ;486(7402):215-21.
Gene structure in the sea urchin Strongylocentrotus purpuratus based on transcriptome analysis. Genome Res. 2012 ;22(10):2079-87.
. Gene therapy rescues cilia defects and restores olfactory function in a mammalian ciliopathy model. Nat Med. 2012 ;18(9):1423-8.
. Genetic contributions to the midsagittal area of the corpus callosum. Twin Res Hum Genet. 2012 ;15(3):315-23.
. Genome sequence of the button mushroom Agaricus bisporus reveals mechanisms governing adaptation to a humic-rich ecological niche. Proc Natl Acad Sci U S A. 2012 ;109(43):17501-6.
. Genome-wide single nucleotide polymorphism arrays as a diagnostic tool in patients with synchronous endometrial and ovarian cancer. Int J Gynecol Cancer. 2012 ;22(5):725-31.
. Genomic and SNP analyses demonstrate a distant separation of the hospital and community-associated clades of Enterococcus faecium. PLoS One. 2012 ;7(1):e30187.
. Genomic sequencing of key genes in mouse pancreatic cancer cells. Curr Mol Med. 2012 ;12(3):331-41.
. Genomics: Gorilla gorilla gorilla. Nature. 2012 ;483(7388):164-5.
. High throughput sequencing methods for microbiome profiling: application to food animal systems. Anim Health Res Rev. 2012 ;13(1):40-53.
. Human genome sequencing in health and disease. Annu Rev Med. 2012 ;63:35-61.
. Identical genomic organization of two hemichordate hox clusters. Curr Biol. 2012 ;22(21):2053-8.
. Identification of a single-stranded DNA virus associated with citrus chlorotic dwarf disease, a new member in the family Geminiviridae. Virology. 2012 ;432(1):162-72.
. Identity and function of a large gene network underlying mutagenic repair of DNA breaks. Science. 2012 ;338(6112):1344-8.
. Increasing the number of URMS in genomic science; (1854F). In 62nd Annual Meeting of The American Society of Human Genetics. San Francisco, California; 2012.
. Integrated analyses of microRNAs demonstrate their widespread influence on gene expression in high-grade serous ovarian carcinoma. PLoS One. 2012 ;7(3):e34546.
. An integrated map of genetic variation from 1,092 human genomes. Nature. 2012 ;491(7422):56-65.
. An integrative variant analysis suite for whole exome next-generation sequencing data. BMC Bioinformatics. 2012 ;13:8.
. The KAT6B-related disorders genitopatellar syndrome and Ohdo/SBBYS syndrome have distinct clinical features reflecting distinct molecular mechanisms. Hum Mutat. 2012 ;33(11):1520-5.
. Landscape of somatic retrotransposition in human cancers. Science. 2012 ;337(6097):967-71.
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