Bioinformatics Programmer I

Vacancy number: 
Human Genome Sequencing Center
Salary range: 
Texas Medical Center, Houston, TX

Job Purpose

This  position with the Next-Generation Sequencing Informatics (NGSI) group requires a Bioinformatics Programmer with Linux/Unix command line and coding experience. As the HGSC's Bioinformatics Core, NGSI manages the production, maintenance, and primary analysis of all genome sequencing data at the HGSC, including Illumina HiSeq X and NovaSeq informatics. NGSI also contributes to multiple clinical, Mendelian, and large cohort sequencing studies, specifically in the areas of structural variation and at-scale genomic data science. Under the direction of a senior manager, a qualified candidate will assist with running research informatics pipelines, managing data storage and delivery, and troubleshooting routine production issues.

Job Duties

  • Manage the generation, storage and delivery of large-sample genomic datasets
  • Develop, test and deploy at-scale analysis protocols
  • Deliver QC'ed data to public repositories and collaborators
  • Maintain extensive project-specific documentation and best practices
  • Support day-to-day NGSI production pipelines
  • Participate in calls and meetings with collaborators
  • Identify novel ways to improve data quality and analysis
  • Provide excellent customer service to other HGSC groups and outside collaborators through ticketing systems

Minimum Qualifications

  • Education Required: Bachelor's degree in Computer Science, Biological Science, or a related field.
  • Experience Required: None Required.
  • Certification/Licenses/Registration: None Required.

Preferred Qualifications

  • Education Preferred: Master’s degree in a related field.

Additional Skills

  • Expert proficiency in Unix environments
  • Proficiency in scripting and automation language (e.g., python, bash)
  • Next-Gen Sequencing analysis tools (e.g., BWA, vcftools, BEDtools, bamUtils, SAMtools, Picard)
  • Common genomics data formats in genomics (e.g., FASTQ, BAM, VCF)
  • High-level ability to manage multiple tasks and overlapping deadlines
  • Demonstrated exceptional written and verbal communication skills