Human Genome Project

Human crowd
Image source: Fady Habib (http://www.flickr.com/photos/untitlism/22800371/) [CC-BY-2.0 or CC-BY-SA-2.0], via Wikimedia Commons

About the Project

The Human Genome Project (HGP) is an international effort to sequence and annotate the entire estimated 3.3 billion bases of the human genome. The project was conceived in the mid-80s, and it began in 1990.

Read more about this project in nature: Initial sequencing and analysis of the human genome

The major contributors for this project include:

The most recent development stemming from HGP is HapMap 3 and Encode 3. Trace data from the HAPMAP Project may be found at TraceArchive for HAPMAP.

The first HGP effort at the BCM-HGSC was completed in 2006, with chromosomes 3, 12 and 30 Mb of X (~10% of the genome). We performed manual annotation and analysis according to Human Annotation Workshop (HAWK) standards, adding hundreds of gene models to those produced by Ensembl analysis. These annotations are available through Vega (see below). Following further analysis the results were published. We used chromosome 12 for our work in the HapMap Project, in expression studies via NimbleGen oligo arrays, and in development of novel genetic analysis tools with Dr. John Belmont. The sequence data and annotations can be viewed with Genboree.

April 14, 2003—International Consortium Completes Human Genome Project

Funding for the Human Genome Project is provided by NIH NHGRI and DOE OBER.

To learn more about the anticipated benefits of the Human Genome Project, go to our information page.

A three-way comparison of mouse and rat to human chromosomes found using Pash is available for browsing.

Our work with chromosomes 3, 12, and X, is described in papers that were recently published in Nature. Please see the citations in the "Publications" section below.

International Genome Consortium Database

Genomic Resources

Citation

All finished data sent to GenBank should be cited according to GenBank's guidelines.