Mouse Genome Project

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Image source: George Shuklin (Own work) [CC-BY-SA-1.0], via Wikimedia Commons

About the Project

The BCM-HGSC has sequenced chromosomes 6 and 10 of the laboratory mouse (Mus musculus).

The genome sequence of the mouse was produced by the Mouse Genome Sequencing Consortium. BCM-HGSC finished 178Mb of redundant sequence or ~120 Mb of unique sequence for the mouse project that was completed in December 2005.

Funding for this project was provided by the NIH.

Genomic Resources

Access to the Data

Individual matched sequences (reads or assemblies) can be retrieved from the BCM-HGSC FTP site or from the NCBI Trace Archive using links below.

A three-way comparison of rat and human to mouse chromosomes found using Pash is available for browsing.

Additional Resources

Related Publications

Larsen PA, Harris RA, Liu Y, Murali SC, C Campbell R, Brown AD, et al. Hybrid de novo genome assembly and centromere characterization of the gray mouse lemur (Microcebus murinus). BMC Biol. 2017 ;15(1):110.

Halim D, Brosens E, Muller F, Wangler MF, Beaudet AL, Lupski JR, et al. Loss-of-Function Variants in MYLK Cause Recessive Megacystis Microcolon Intestinal Hypoperistalsis Syndrome. Am J Hum Genet. 2017 ;101(1):123-129.

Stitziel NO, Khera AV, Wang X, Bierhals AJ, A Vourakis C, Sperry AE, et al. ANGPTL3 Deficiency and Protection Against Coronary Artery Disease. J Am Coll Cardiol. 2017 ;69(16):2054-2063.

Agrawal SA, Burgoyne T, Eblimit A, Bellingham J, Parfitt DA, Lane A, et al. REEP6 deficiency leads to retinal degeneration through disruption of ER homeostasis and protein trafficking. Hum Mol Genet. 2017 ;26(14):2667-2677.

Nargund AM, Pham CG, Dong Y, Wang PI, Osmangeyoglu HU, Xie Y, et al. The SWI/SNF Protein PBRM1 Restrains VHL-Loss-Driven Clear Cell Renal Cell Carcinoma. Cell Rep. 2017 ;18(12):2893-2906.

Worley KC. A golden goat genome. Nat Genet. 2017 ;49(4):485-486.

Xu M, Xie YAngela, Abouzeid H, Gordon CT, Fiorentino A, Sun Z, et al. Mutations in the Spliceosome Component CWC27 Cause Retinal Degeneration with or without Additional Developmental Anomalies. Am J Hum Genet. 2017 ;100(4):592-604.

Lu H-C, Tan Q, Rousseaux MWC, Wang W, Kim J-Y, Richman R, et al. Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans. Nat Genet. 2017 ;49(4):527-536.