Mouse Genome Project

Image source: George Shuklin (Own work) [CC-BY-SA-1.0], via Wikimedia Commons

About the Project

The BCM-HGSC has sequenced chromosomes 6 and 10 of the laboratory mouse (Mus musculus).

The genome sequence of the mouse was produced by the Mouse Genome Sequencing Consortium. BCM-HGSC finished 178Mb of redundant sequence or ~120 Mb of unique sequence for the mouse project that was completed in December 2005.

Funding for this project was provided by the NIH.

Genomic Resources

Access to the Data

Individual matched sequences (reads or assemblies) can be retrieved from the BCM-HGSC FTP site or from the NCBI Trace Archive using links below.

A three-way comparison of rat and human to mouse chromosomes found using Pash is available for browsing.

Additional Resources

Related Publications

Willmore KE, Roseman CC, Rogers J, Cheverud JM, Richtsmeier JT. Comparison of Mandibular Phenotypic and Genetic Integration between Baboon and Mouse. Evol Biol. 2009 ;36(1):19-36.

Wang H, Hollander AI den, Moayedi Y, Abulimiti A, Li Y, Collin RWJ, et al.. Mutations in SPATA7 cause Leber congenital amaurosis and juvenile retinitis pigmentosa. Am J Hum Genet. 2009 ;84(3):380-7.

Garbow JR, Wang M, Wang Y, Lubet RA, You M. Quantitative monitoring of adenocarcinoma development in rodents by magnetic resonance imaging. Clin Cancer Res. 2008 ;14(5):1363-7.

Cheverud JM, Hager R, Roseman C, Fawcett G, Wang B, Wolf JB. Genomic imprinting effects on adult body composition in mice. Proc Natl Acad Sci U S A. 2008 ;105(11):4253-8.

Kenney-Hunt JP, Wang B, Norgard EA, Fawcett G, Falk D, L Pletscher S, et al.. Pleiotropic patterns of quantitative trait loci for 70 murine skeletal traits. Genetics. 2008 ;178(4):2275-88.

Norgard EA, Roseman CC, Fawcett GL, Pavlicev M, Morgan CD, L Pletscher S, et al.. Identification of quantitative trait loci affecting murine long bone length in a two-generation intercross of LG/J and SM/J Mice. J Bone Miner Res. 2008 ;23(6):887-95.

Bourgogne A, Garsin DA, Qin X, Singh KV, Sillanpaa J, Yerrapragada S, et al.. Large scale variation in Enterococcus faecalis illustrated by the genome analysis of strain OG1RF. Genome Biol. 2008 ;9(7):R110.

Reid JG, Nagaraja AK, Lynn FC, Drabek RB, Muzny DM, Shaw CA, et al.. Mouse let-7 miRNA populations exhibit RNA editing that is constrained in the 5'-seed/ cleavage/anchor regions and stabilize predicted mmu-let-7a:mRNA duplexes. Genome Res. 2008 ;18(10):1571-81.

Liu S, Ballian N, Belaguli NS, Patel S, Li M, Templeton NSmyth, et al.. PDX-1 acts as a potential molecular target for treatment of human pancreatic cancer. Pancreas. 2008 ;37(2):210-20.

Wang M, Vikis HG, Wang Y, Jia D, Wang D, Bierut LJ, et al.. Identification of a novel tumor suppressor gene p34 on human chromosome 6q25.1. Cancer Res. 2007 ;67(1):93-9.