Mouse Genome Project

Image source: George Shuklin (Own work) [CC-BY-SA-1.0], via Wikimedia Commons

About the Project

The BCM-HGSC has sequenced chromosomes 6 and 10 of the laboratory mouse (Mus musculus).

The genome sequence of the mouse was produced by the Mouse Genome Sequencing Consortium. BCM-HGSC finished 178Mb of redundant sequence or ~120 Mb of unique sequence for the mouse project that was completed in December 2005.

Funding for this project was provided by the NIH.

Genomic Resources

Access to the Data

Individual matched sequences (reads or assemblies) can be retrieved from the BCM-HGSC FTP site or from the NCBI Trace Archive using links below.

A three-way comparison of rat and human to mouse chromosomes found using Pash is available for browsing.

Additional Resources

Related Publications

Oeltjen JC, Malley TM, Muzny DM, Miller W, Gibbs RA, Belmont JW. Large-scale comparative sequence analysis of the human and murine Bruton's tyrosine kinase loci reveals conserved regulatory domains. Genome Res. 1997 ;7(4):315-29.

Levin ML, Chatterjee A, Pragliola A, Worley KC, Wehnert M, Zhuchenko O, et al.. A comparative transcription map of the murine bare patches (Bpa) and striated (Str) critical regions and human Xq28. Genome Res. 1996 ;6(6):465-77.

Jones SN, Ansari-Lari MA, Hancock AR, Jones WJ, Gibbs RA, Donehower LA, et al.. Genomic organization of the mouse double minute 2 gene. Gene. 1996 ;175(1-2):209-13.

Shinbrot E, Peters KG, Williams LT. Expression of the platelet-derived growth factor beta receptor during organogenesis and tissue differentiation in the mouse embryo. Dev Dyn. 1994 ;199(3):169-75.

Zheng H, Hasty P, Brenneman MA, Grompe M, Gibbs RA, Wilson JH, et al.. Fidelity of targeted recombination in human fibroblasts and murine embryonic stem cells. Proc Natl Acad Sci U S A. 1991 ;88(18):8067-71.

Gingras M-C, Szpirer J, Turcotte B, Bélanger L, Szpirer C. Differential regulation of normal and tumor alpha 1-fetoprotein genes in fetal hepatocyte x hepatoma hybrids. Cancer Res. 1988 ;48(22):6371-4.

Scherer SE, Veres G, Caskey CT. The genetic structure of mouse ornithine transcarbamylase. Nucleic Acids Res. 1988 ;16(4):1593-601.

Chamberlain JS, Pearlman JA, Muzny DM, Gibbs RA, Ranier JE, Caskey CT, et al.. Expression of the murine Duchenne muscular dystrophy gene in muscle and brain. Science. 1988 ;239(4846):1416-8.

Veres G, Gibbs RA, Scherer SE, Caskey CT. The molecular basis of the sparse fur mouse mutation. Science. 1987 ;237(4813):415-7.