Mouse Genome Project

Image source: George Shuklin (Own work) [CC-BY-SA-1.0], via Wikimedia Commons

About the Project

The BCM-HGSC has sequenced chromosomes 6 and 10 of the laboratory mouse (Mus musculus).

The genome sequence of the mouse was produced by the Mouse Genome Sequencing Consortium. BCM-HGSC finished 178Mb of redundant sequence or ~120 Mb of unique sequence for the mouse project that was completed in December 2005.

Funding for this project was provided by the NIH.

Genomic Resources

Access to the Data

Individual matched sequences (reads or assemblies) can be retrieved from the BCM-HGSC FTP site or from the NCBI Trace Archive using links below.

A three-way comparison of rat and human to mouse chromosomes found using Pash is available for browsing.

Additional Resources

Related Publications

Dinckan N, Du R, Akdemir ZC, Bayram Y, Jhangiani SN, Doddapaneni H, et al.. A biallelic ANTXR1 variant expands the anthrax toxin receptor associated phenotype to tooth agenesis. Am J Med Genet A. 2018 ;176(4):1015-1022.

Guo L, Akahori H, Harari E, Smith SL, Polavarapu R, Karmali V, et al.. CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis. J Clin Invest. 2018 ;128(3):1106-1124.

Eblimit A, Zaneveld SAgrawal, Liu W, Thomas K, Wang K, Li Y, et al.. NMNAT1 E257K variant, associated with Leber Congenital Amaurosis (LCA9), causes a mild retinal degeneration phenotype. Exp Eye Res. 2018 ;173:32-43.

Baker K, Gordon SL, Melland H, Bumbak F, Scott DJ, Jiang TJ, et al.. SYT1-associated neurodevelopmental disorder: a case series. Brain. 2018 ;141(9):2576-2591.

Dray BK, Raveendran M, Harris RA, Benavides F, Gray SB, Perez CJ, et al.. Mismatch repair gene mutations lead to lynch syndrome colorectal cancer in rhesus macaques. Genes Cancer. 2018 ;9(3-4):142-152.

Zhang L, Sun Z, Zhao P, Huang L, Xu M, Yang Y, et al.. Whole-exome sequencing revealed HKDC1 as a candidate gene associated with autosomal-recessive retinitis pigmentosa. Hum Mol Genet. 2018 ;27(23):4157-4168.

Nargund AM, Pham CG, Dong Y, Wang PI, Osmangeyoglu HU, Xie Y, et al.. The SWI/SNF Protein PBRM1 Restrains VHL-Loss-Driven Clear Cell Renal Cell Carcinoma. Cell Rep. 2017 ;18(12):2893-2906.

Worley KC. A golden goat genome. Nat Genet. 2017 ;49(4):485-486.

Lu H-C, Tan Q, Rousseaux MWC, Wang W, Kim J-Y, Richman R, et al.. Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans. Nat Genet. 2017 ;49(4):527-536.

Xu M, Xie YAngela, Abouzeid H, Gordon CT, Fiorentino A, Sun Z, et al.. Mutations in the Spliceosome Component CWC27 Cause Retinal Degeneration with or without Additional Developmental Anomalies. Am J Hum Genet. 2017 ;100(4):592-604.