Researchers from the Human Genome Sequencing Center and the Elkins Pancreas Center at Baylor College of Medicine have collaborated with researchers in the United Kingdom and Australia in a breakthrough reclassification of pancreatic cancer, offering new opportunities to treat the often-fatal disease. Their report was published online Feb. 24 in Nature.
Through the study, whole genome sequencing was performed on more than 450 patients with pancreatic cancer. Several new genes involved in the disease were identified. Most importantly, the study found four key subtypes of the cancer, with each possessing their own distinct clinical characteristics and differential survival outcomes.