Non-Human Primate Genome Sequencing

Image source: Charlesjsharp (Own work) [CC-BY-SA-3.0], via Wikimedia Commons
 

The BCM-HGSC is sequencing genomes from representative species from most of the major branches of the phylogeny: hominoids (Homo, Pongo, Nomascus), Old World monkeys (Papio, Macaca, Cercocebus), New World monkeys (Callithrix) and lemurs (Microcebus).

Current sequencing efforts all include diversity panels investigating within-species variation or closely related species or subspecies. For example, the diversity panel for the white-cheeked gibbon (Nomascus) will include Hylobates, Symphalangus, and Bunopithecus.

This phylogeny below of the primates is color coded (completed genome=purple, draft completed=blue, sequencing in progress=red, diversity panel species=gold) to display genome analyses being performed at Baylor College of Medicine’s Human Genome Sequencing Center (BCM-HGSC) (phylogeny adapted from Perelman P, et al. PLoS Genetics (2011) 7(3): e1001342).

 

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