David Wheeler, Ph.D.

Professor, Department of Molecular and Human Genetics

image: David Wheeler, Ph.D.Contact Information

wheeler@bcm.edu

Publications

2011
Davis EE, Zhang Q, Liu Q, Diplas BH, Davey LM, Hartley J, et al.. TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum. Nat Genet. 2011;43(3):189-96.

Klassen T, Davis C, Goldman A, Burgess D, Chen T, Wheeler DA, et al.. Exome sequencing of ion channel genes reveals complex profiles confounding personal risk assessment in epilepsy. Cell. 2011;145(7):1036-48.

Fawcett GL, Raveendran M, Deiros DRio, Chen D, Yu F, Harris RA, et al.. Characterization of single-nucleotide variation in Indian-origin rhesus macaques (Macaca mulatta). BMC Genomics. 2011;12:311.

Plon SE, Wheeler DA, Strong LC, Tomlinson GE, Pirics M, Meng Q, et al.. Identification of genetic susceptibility to childhood cancer through analysis of genes in parallel. Cancer Genet. 2011;204(1):19-25.

Agrawal N, Frederick MJ, Pickering CR, Bettegowda C, Chang K, Li RJ, et al.. Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science. 2011;333(6046):1154-7.

Harring TR, Guiteau JJ, N Nguyen TT, Cotton RT, Gingras M-C, Wheeler DA, et al.. Building a comprehensive genomic program for hepatocellular carcinoma. World J Surg. 2011;35(8):1746-50.

N Nguyen TT, Cotton RT, Harring TR, Guiteau JJ, Gingras M-C, Wheeler DA, et al.. A primer on a hepatocellular carcinoma bioresource bank using the cancer genome atlas guidelines: practical issues and pitfalls. World J Surg. 2011;35(8):1732-7.

2010
Altshuler DM, Gibbs RA, Peltonen L, Altshuler DM, Gibbs RA, Peltonen L, et al.. Integrating common and rare genetic variation in diverse human populations. Nature. 2010;467(7311):52-8.

Shen Y, Wan Z, Coarfa C, Drabek R, Chen L, Ostrowski EA, et al.. A SNP discovery method to assess variant allele probability from next-generation resequencing data. Genome Res. 2010;20(2):273-80.

Lupski JR, Reid JG, Gonzaga-Jauregui C, Deiros DRio, C Y Chen D, Nazareth L, et al.. Whole-genome sequencing in a patient with Charcot-Marie-Tooth neuropathy. N Engl J Med. 2010;362(13):1181-91.

2009
Maheshwari M, Shi J, Badner JA, Skol A, Willour VL, Muzny DM, et al.. Common and rare variants of DAOA in bipolar disorder. Am J Med Genet B Neuropsychiatr Genet. 2009;150B(7):960-6.

Guo D-chuan, Papke CL, Tran-Fadulu V, Regalado ES, Avidan N, Johnson RJay, et al.. Mutations in smooth muscle alpha-actin (ACTA2) cause coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic disease. Am J Hum Genet. 2009;84(5):617-27.

Khanna H, Davis EE, Murga-Zamalloa CA, Estrada-Cuzcano A, Lopez I, Hollander AI den, et al.. A common allele in RPGRIP1L is a modifier of retinal degeneration in ciliopathies. Nat Genet. 2009;41(6):739-45.

Elsik CG, Tellam RL, Worley KC, Gibbs RA, Muzny DM, Weinstock GM, et al.. The genome sequence of taurine cattle: a window to ruminant biology and evolution. Science. 2009;324(5926):522-8.

Gibbs RA, Taylor JF, Van Tassell CP, Barendse W, Eversole KA, Gill CA, et al.. Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds. Science. 2009;324(5926):528-32.

2008
Ding L, Getz G, Wheeler DA, Mardis ER, McLellan MD, Cibulskis K, et al.. Somatic mutations affect key pathways in lung adenocarcinoma. Nature. 2008;455(7216):1069-75.

Gu P, Reid JG, Gao X, Shaw CA, Creighton CJ, Tran PL, et al.. Novel microRNA candidates and miRNA-mRNA pairs in embryonic stem (ES) cells. PLoS One. 2008;3(7):e2548.

Wheeler DA, Srinivasan M, Egholm M, Shen Y, Chen L, McGuire A, et al.. The complete genome of an individual by massively parallel DNA sequencing. Nature. 2008;452(7189):872-6.

2007
Sabeti PC, Varilly P, Fry B, Lohmueller J, Hostetter E, Cotsapas C, et al.. Genome-wide detection and characterization of positive selection in human populations. Nature. 2007;449(7164):913-8.

Frazer KA, Ballinger DG, Cox DR, Hinds DA, Stuve LL, Gibbs RA, et al.. A second generation human haplotype map of over 3.1 million SNPs. Nature. 2007;449(7164):851-61.