David Wheeler, Ph.D.

Professor, Department of Molecular and Human Genetics

image: David Wheeler, Ph.D.Contact Information

wheeler@bcm.edu

Publications

2007
Albert TJ, Molla MN, Muzny DM, Nazareth L, Wheeler DA, Song X, et al.. Direct selection of human genomic loci by microarray hybridization. Nat Methods. 2007;4(11):903-5.

Birney E, Stamatoyannopoulos JA, Dutta A, Guigó R, Gingeras TR, Margulies EH, et al.. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature. 2007;447(7146):799-816.

Margulies EH, Cooper GM, Asimenos G, Thomas DJ, Dewey CN, Siepel A, et al.. Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome. Genome Res. 2007;17(6):760-74.

Weir BA, Woo MS, Getz G, Perner S, Ding L, Beroukhim R, et al.. Characterizing the cancer genome in lung adenocarcinoma. Nature. 2007;450(7171):893-8.

Hernandez RD, Hubisz MJ, Wheeler DA, Smith DG, Ferguson B, Rogers J, et al.. Demographic histories and patterns of linkage disequilibrium in Chinese and Indian rhesus macaques. Science. 2007;316(5822):240-3.

Gibbs RA, Rogers J, Katze MG, Bumgarner R, Weinstock GM, Mardis ER, et al.. Evolutionary and biomedical insights from the rhesus macaque genome. Science. 2007;316(5822):222-34.

2006
Zhao Y, Yang Z, Phelan JK, Wheeler DA, Lin S, McCabe ERB. Zebrafish dax1 is required for development of the interrenal organ, the adrenal cortex equivalent. Mol Endocrinol. 2006;20(11):2630-40.

Scherer SE, Muzny DM, Buhay CJ, Chen R, Cree A, Ding Y, et al.. The finished DNA sequence of human chromosome 12. Nature. 2006;440(7082):346-51.

Mukherjee A, Soyal SM, Wheeler DA, Fernández-Valdivia R, Nguyen J, DeMayo FJ, et al.. Targeting iCre expression to murine progesterone receptor cell-lineages using bacterial artificial chromosome transgenesis. Genesis. 2006;44(12):601-10.

Muzny DM, Scherer SE, Kaul R, Wang J, Yu J, Sudbrak R, et al.. The DNA sequence, annotation and analysis of human chromosome 3. Nature. 2006;440(7088):1194-8.

2005
Zhang J, Wheeler DA, Yakub I, Wei S, Sood R, Rowe W, et al.. SNPdetector: a software tool for sensitive and accurate SNP detection. PLoS Comput Biol. 2005;1(5):e53.

Gu P, LeMenuet D, Chung AC-K, Mancini M, Wheeler DA, Cooney AJ. Orphan nuclear receptor GCNF is required for the repression of pluripotency genes during retinoic acid-induced embryonic stem cell differentiation. Mol Cell Biol. 2005;25(19):8507-19.

Gu P, Goodwin B, Chung AC-K, Xu X, Wheeler DA, Price RR, et al.. Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development. Mol Cell Biol. 2005;25(9):3492-505.

Ross MT, Grafham DV, Coffey AJ, Scherer SE, McLay K, Muzny DM, et al.. The DNA sequence of the human X chromosome. Nature. 2005;434(7031):325-37.

Richards S, Liu Y, Bettencourt BR, Hradecky P, Letovsky S, Nielsen R, et al.. Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution. Genome Res. 2005;15(1):1-18.

2004
Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer SE, et al.. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature. 2004;428(6982):493-521.

Zhang Z, Burch PE, Cooney AJ, Lanz RB, Pereira FA, Wu J, et al.. Genomic analysis of the nuclear receptor family: new insights into structure, regulation, and evolution from the rat genome. Genome Res. 2004;14(4):580-90.

2002
Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, et al.. Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence. Genome Biol. 2002;3(12):RESEARCH0079.

1996
Fowler J, Wheeler DA, Camerino PW, Bat O, Burch PE. Development of a faculty research interest resource. Proc AMIA Annu Fall Symp. 1996;:363-7.

1993
Guo W, Worley KC, Adams V, Mason J, Sylvester-Jackson D, Zhang YH, et al.. Genomic scanning for expressed sequences in Xp21 identifies the glycerol kinase gene. Nat Genet. 1993;4(4):367-72.