About the Project
Image source: Wikimedia Commons
The BCM-HGSC is sequencing the genome of the tammar wallaby (Macropus eugenii) as part of the Tammar Wallaby Genome Sequencing Consortium, a collaboration between the BCM-HGSC and the Australian Genome Research Facility Ltd. (AGRF).
The goal of the project is to produce a two-fold coverage draft sequence by whole genome shotgun sequencing. The project will expand existing wallaby genetic resources and explore the unique biological features of this marsupial, centered on reproduction, fertility, seasonal breeding, pregnancy, lactation, sex determination and differentiation.
DNA for construction of WGS libraries was isolated from a female wallaby lung (from AGRF). A male tammar wallaby BAC library was made at the Arizona Genomics Institute. There has been a great deal of interaction and visits between the BCM-HGSC and AGRF teams from the outset, including exchange of protocols and reagents. An initial low-coverage assembly is available.
The Tammar wallaby genome project is funded by the National Human Genome Research Institute (NHGRI), National Institutes of Health (NIH), the Australian Genome Research Facility Ltd. (AGRF), The Victorian State Government, and the Brockhoff Foundation.
Access to the data
Version 1.1 of the assembly, Meug_1.1 is available for download. The assembly is described in detail in the README in that directory.
Meug_1.1 is a preliminary genome assembly that includes small insert paired end information from ABI Sanger and SOLiD technologies. This version of the assembly does not include repetitive sequences and has not been localized to chromosomes.
Sanger traces are available from the NCBI Trace Archive, which can be searched using NCBI MegaBLAST with a same species or cross species query.
SOLiD sequences are available from the NCBI Short Read Archive.
Renfree MB, et al. Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development. Genome Biol. 2011 Aug 29;12(8):R81. PMID: 21854559.