Mouse Genome Project

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Image source: George Shuklin (Own work) [CC-BY-SA-1.0], via Wikimedia Commons

About the Project

The BCM-HGSC has sequenced chromosomes 6 and 10 of the laboratory mouse (Mus musculus).

The genome sequence of the mouse was produced by the Mouse Genome Sequencing Consortium. BCM-HGSC finished 178Mb of redundant sequence or ~120 Mb of unique sequence for the mouse project that was completed in December 2005.

Funding for this project was provided by the NIH.

Genomic Resources

Access to the Data

Individual matched sequences (reads or assemblies) can be retrieved from the BCM-HGSC FTP site or from the NCBI Trace Archive using links below.

A three-way comparison of rat and human to mouse chromosomes found using Pash is available for browsing.

Additional Resources

Related Publications

Zaneveld SAgrawal, Eblimit A, Liang Q, Bertrand R, Wu N, Liu H, et al. Gene Therapy Rescues Retinal Degeneration in Reep6 Mutant Mice. Hum Gene Ther. 2018 ;.

Baker K, Gordon SL, Melland H, Bumbak F, Scott DJ, Jiang TJ, et al. SYT1-associated neurodevelopmental disorder: a case series. Brain. 2018 ;.

Dray BK, Raveendran M, R Harris A, Benavides F, Gray SB, Perez CJ, et al. Mismatch repair gene mutations lead to lynch syndrome colorectal cancer in rhesus macaques. Genes Cancer. 2018 ;9(3-4):142-152.

Eblimit A, Zaneveld SAgrawal, Liu W, Thomas K, Wang K, Li Y, et al. NMNAT1 E257K variant, associated with Leber Congenital Amaurosis (LCA9), causes a mild retinal degeneration phenotype. Exp Eye Res. 2018 ;173:32-43.

Guo L, Akahori H, Harari E, Smith SL, Polavarapu R, Karmali V, et al. CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis. J Clin Invest. 2018 ;128(3):1106-1124.

Dinckan N, Du R, Akdemir ZC, Bayram Y, Jhangiani SN, Doddapaneni HV, et al. A biallelic ANTXR1 variant expands the anthrax toxin receptor associated phenotype to tooth agenesis. Am J Med Genet A. 2018 ;176(4):1015-1022.

McClard CK, Kochukov MY, Herman I, Liu Z, Eblimit A, Moayedi Y, et al. POU6f1 Mediates Neuropeptide-Dependent Plasticity in the Adult Brain. J Neurosci. 2018 ;38(6):1443-1461.

Eblimit A, Agrawal SAkshay, Thomas K, Anastassov IAssenov, Abulikemu T, Mardon G, et al. Conditional loss of Spata7 in photoreceptors causes progressive retinal degeneration in mice. Exp Eye Res. 2018 ;166:120-130.

Larsen PA, R Harris A, Liu Y, Murali SC, C Campbell R, Brown AD, et al. Hybrid de novo genome assembly and centromere characterization of the gray mouse lemur (Microcebus murinus). BMC Biol. 2017 ;15(1):110.