Mouse Genome Project

Image source: George Shuklin (Own work) [CC-BY-SA-1.0], via Wikimedia Commons

About the Project

The BCM-HGSC has sequenced chromosomes 6 and 10 of the laboratory mouse (Mus musculus).

The genome sequence of the mouse was produced by the Mouse Genome Sequencing Consortium. BCM-HGSC finished 178Mb of redundant sequence or ~120 Mb of unique sequence for the mouse project that was completed in December 2005.

Funding for this project was provided by the NIH.

Genomic Resources

Access to the Data

Individual matched sequences (reads or assemblies) can be retrieved from the BCM-HGSC FTP site or from the NCBI Trace Archive using links below.

A three-way comparison of rat and human to mouse chromosomes found using Pash is available for browsing.

Additional Resources

Related Publications

Ullah E, Lin S, Lu J, Bender C, Webster AR, Malka S, et al.. Biallelic Loss-of-Function Variants in UBAP1L and Nonsyndromic Retinal Dystrophies. JAMA Ophthalmol. 2024 ;.

Bassani S, Chrast J, Ambrosini G, Voisin N, Schütz F, Brusco A, et al.. Variant-specific pathophysiological mechanisms of AFF3 differently influence transcriptome profiles. medRxiv. 2024 ;.

Yang L, Peery RC, Farmer LM, Gao X, Zhang Y, Creighton CJ, et al.. Dietary Folate and Cofactors Accelerate Age-dependent p16 Epimutation to Promote Intestinal Tumorigenesis. Cancer Res Commun. 2024 ;4(1):164-169.

Li J, Choi J, Cheng X, Ma J, Pema S, Sanes JR, et al.. Comprehensive single-cell atlas of the mouse retina. bioRxiv. 2024 ;.

Bassani S, Chrast J, Ambrosini G, Voisin N, Schütz F, Brusco A, et al.. Variant-specific pathophysiological mechanisms of AFF3 differently influence transcriptome profiles. Genome Med. 2024 ;16(1):72.

Potter AS, Miyake CY, Gonzaga-Jauregui C, Aguilar-Sanchez Y, Hulsurkar MM, Lahiri SK, et al.. Rare Variant in Associated With Familial Supraventricular Tachycardia and Wolff-Parkinson-White Syndrome. Circ Genom Precis Med. 2024 ;17(4):e004614.

Li J, Choi J, Cheng X, Ma J, Pema S, Sanes JR, et al.. Comprehensive single-cell atlas of the mouse retina. iScience. 2024 ;27(6):109916.

Yang L, Chen X, Lee C, Shi J, Lawrence EB, Zhang L, et al.. Functional characterization of age-dependent p16 epimutation reveals biological drivers and therapeutic targets for colorectal cancer. J Exp Clin Cancer Res. 2023 ;42(1):113.

Mao K, Borel C, Ansar M, Jolly A, Makrythanasis P, Froehlich C, et al.. FOXI3 pathogenic variants cause one form of craniofacial microsomia. Nat Commun. 2023 ;14(1):2026.

Weinstock JS, Gopakumar J, Burugula BBharathi, Uddin MMesbah, Jahn N, Belk JA, et al.. Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis. Nature. 2023 ;616(7958):755-763.