Publications
Filters: Keyword is Sequence Analysis, DNA [Clear All Filters]
Characterization and visualization of tandem repeats at genome scale. Nat Biotechnol. 2024 ;42(10):1606-1614.
. Detection of mosaic and population-level structural variants with Sniffles2. Nat Biotechnol. 2024 ;42(10):1571-1580.
. The GIAB genomic stratifications resource for human reference genomes. Nat Commun. 2024 ;15(1):9029.
. Improved high quality sand fly assemblies enabled by ultra low input long read sequencing. Sci Data. 2024 ;11(1):918.
. Improved sequence mapping using a complete reference genome and lift-over. Nat Methods. 2024 ;21(1):41-49.
. StratoMod: predicting sequencing and variant calling errors with interpretable machine learning. Commun Biol. 2024 ;7(1):1316.
. Unveiling microbial diversity: harnessing long-read sequencing technology. Nat Methods. 2024 ;21(6):954-966.
. Utility of long-read sequencing for All of Us. Nat Commun. 2024 ;15(1):837.
. Beyond the exome: What's next in diagnostic testing for Mendelian conditions. Am J Hum Genet. 2023 ;110(8):1229-1248.
. The complete sequence of a human Y chromosome. Nature. 2023 ;621(7978):344-354.
. An efficient genotyper and star-allele caller for pharmacogenomics. Genome Res. 2023 ;33(1):61-70.
. FixItFelix: improving genomic analysis by fixing reference errors. Genome Biol. 2023 ;24(1):31.
. Scalable Nanopore sequencing of human genomes provides a comprehensive view of haplotype-resolved variation and methylation. Nat Methods. 2023 ;20(10):1483-1492.
. Variant calling and benchmarking in an era of complete human genome sequences. Nat Rev Genet. 2023 ;24(7):464-483.
. Accurate profiling of forensic autosomal STRs using the Oxford Nanopore Technologies MinION device. Forensic Sci Int Genet. 2022 ;56:102629.
. A complete reference genome improves analysis of human genetic variation. Science. 2022 ;376(6588):eabl3533.
. The complete sequence of a human genome. Science. 2022 ;376(6588):44-53.
. Curated variation benchmarks for challenging medically relevant autosomal genes. Nat Biotechnol. 2022 ;40(5):672-680.
. Targeted Genome Sequencing Identifies Multiple Rare Variants in Caveolin-1 Associated with Obstructive Sleep Apnea. Am J Respir Crit Care Med. 2022 ;206(10):1271-1280.
. A Validation Framework for Somatic Copy Number Detection in Targeted Sequencing Panels. J Mol Diagn. 2022 ;24(7):760-774.
. Hidden biases in germline structural variant detection. Genome Biol. 2021 ;22(1):347.
. Oligonucleotide capture sequencing of the SARS-CoV-2 genome and subgenomic fragments from COVID-19 individuals. PLoS One. 2021 ;16(8):e0244468.
. Optimized sample selection for cost-efficient long-read population sequencing. Genome Res. 2021 ;31(5):910-918.
. Performance assessment of DNA sequencing platforms in the ABRF Next-Generation Sequencing Study. Nat Biotechnol. 2021 ;39(9):1129-1140.
. PRINCESS: comprehensive detection of haplotype resolved SNVs, SVs, and methylation. Genome Biol. 2021 ;22(1):268.
.