Steve Scherer, Ph.D.

Professor, Department of Molecular and Human Genetics

image: Steve Scherer, Ph.D.Contact information

sscherer@bcm.edu

Publications

2023
Alge JL, Bekheirnia N, Willcockson AR, Qin X, Scherer SE, Braun MC, et al.. Variants in genes coding for collagen type IV α-chains are frequent causes of persistent, isolated hematuria during childhood. Pediatr Nephrol. 2023;38(3):687-695.

Bi W, Yuan B, Liu P, Murry JB, Qin X, Xia F, et al.. Recurring germline mosaicism in a family due to reversion of an inherited derivative chromosome 8 from an 8;21 translocation with interstitial telomeric sequences. J Med Genet. 2023;60(6):547-556.

Hari A, Zhou Q, Gonzaludo N, Harting J, Scott SA, Qin X, et al.. An efficient genotyper and star-allele caller for pharmacogenomics. Genome Res. 2023;33(1):61-70.

2022
Wang L, Scherer SE, Bielinski SJ, Muzny DM, Jones LA, Black JLogan, et al.. Implementation of preemptive DNA sequence-based pharmacogenomics testing across a large academic medical center: The Mayo-Baylor RIGHT 10K Study. Genet Med. 2022;24(5):1062-1072.

Lopes JL, Harris K, Karow MBeth, Peterson SE, Kluge ML, Kotzer KE, et al.. Targeted Genotyping in Clinical Pharmacogenomics: What Is Missing?. J Mol Diagn. 2022;24(3):253-261.

Langlois AWR, El-Boraie A, Fukunaga K, Mushiroda T, Kubo M, Lerman C, et al.. Accuracy and applications of sequencing and genotyping approaches for CYP2A6 and homologous genes. Pharmacogenet Genomics. 2022;32(4):159-172.

Gaedigk A, Boone EC, Scherer SE, Lee S-B, Numanagić I, Sahinalp C, et al.. CYP2C8, CYP2C9, and CYP2C19 Characterization Using Next-Generation Sequencing and Haplotype Analysis: A GeT-RM Collaborative Project. J Mol Diagn. 2022;24(4):337-350.

2021
Henderson YC, Mohamed ASR, Maniakas A, Chen Y, Powell RT, Peng S, et al.. A High-throughput Approach to Identify Effective Systemic Agents for the Treatment of Anaplastic Thyroid Carcinoma. J Clin Endocrinol Metab. 2021;106(10):2962-2978.

Maniakas A, Henderson YC, Hei H, Peng S, Chen Y, Jiang Y, et al.. Novel Anaplastic Thyroid Cancer PDXs and Cell Lines: Expanding Preclinical Models of Genetic Diversity. J Clin Endocrinol Metab. 2021;106(11):e4652-e4665.

2019
Midro AT, Tommerup N, Borys J, Panasiuk B, Kosztyła-Hojna B, Zalewska R, et al.. Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies syndrome due to disruption of BPTF in a 35-year-old man initially diagnosed with Silver-Russell syndrome. Clin Genet. 2019;95(4):534-536.

2016
McGuire AL, Moore Q, Majumder M, Walkiewicz M, Eng CM, Belmont JW, et al.. The ethics of conducting molecular autopsies in cases of sudden death in the young. Genome Res. 2016;26(9):1165-9.

2015
Zhao C, Escalante LNavarro, Chen H, Benatti TR, Qu J, Chellapilla S, et al.. A massive expansion of effector genes underlies gall-formation in the wheat pest Mayetiola destructor. Curr Biol. 2015;25(5):613-20.

2008
Richards S, Gibbs RA, Weinstock GM, Brown SJ, Denell R, Beeman RW, et al.. The genome of the model beetle and pest Tribolium castaneum. Nature. 2008;452(7190):949-55.

2007
Guo D-chuan, Pannu H, Tran-Fadulu V, Papke CL, Yu RK, Avidan N, et al.. Mutations in smooth muscle alpha-actin (ACTA2) lead to thoracic aortic aneurysms and dissections. Nat Genet. 2007;39(12):1488-93.

2006
Kim M-S, Jeong J, Majewski T, Kram A, Yoon D-S, Zhang R-D, et al.. Evidence for alternative candidate genes near RB1 involved in clonal expansion of in situ urothelial neoplasia. Lab Invest. 2006;86(2):175-90.

Muzny DM, Scherer SE, Kaul R, Wang J, Yu J, Sudbrak R, et al.. The DNA sequence, annotation and analysis of human chromosome 3. Nature. 2006;440(7088):1194-8.

2005
Alford RL, Morris KE, Rives CM, Scherer SE, Weinstock G, Gibbs RA, et al.. Genetic testing, biotechnology, and GMOs: A snapshot of public opinion, 2003 through 2004. Genet Med. 2005;7(6):454-5.

2002
Scott GBI, Steffen DL, Edgar D, Warren JT, Kovár CL, Scherer SE, et al.. Loader Lite: a new software tool for the ABI PRISM 3700 DNA sequencer. Biotechniques. 2002;32(6):1366, 1368, 1370-1.

2001
Chew LJ, Yuan X, Scherer SE, Qie L, Huang F, Hayes WP, et al.. Characterization of the rat GRIK5 kainate receptor subunit gene promoter and its intragenic regions involved in neural cell specificity. J Biol Chem. 2001;276(45):42162-71.

2000
Hoskins RA, Nelson CR, Berman BP, Laverty TR, George RA, Ciesiolka L, et al.. A BAC-based physical map of the major autosomes of Drosophila melanogaster. Science. 2000;287(5461):2271-4.