R. Alan Harris, Ph.D.

Assistant Professor, Department of Molecular and Human Genetics

harris-ra_225x250.png Contact information

rharris1@bcm.edu

Education

Postdoc, Molecular and Human Genetics, Baylor College Of Medicine, Houston, 2009

Ph.D., Molecular and Human Genetics, Baylor College Of Medicine, Houston, 2007

M.A., Biological Anthropology, Kent State University, Kent, Ohio, 1996

B.A., Anthropology, Geology, Florida State University, Tallahassee, Florida, 1990

Publications

2024
Prall TM, Karl JA, Varghese JM, Baker DA, Minor NR, Raveendran M, et al.. Complete Genomic Assembly of Mauritian Cynomolgus Macaque Killer Ig-like Receptor and Natural Killer Group 2 Haplotypes. J Immunol. 2024;212(11):1754-1765.

Wang J, Wang M, Moshiri A, Harris RA, Raveendran M, Nguyen T, et al.. Genetic diversity of 1,845 rhesus macaques improves genetic variation interpretation and identifies disease models. Nat Commun. 2024;15(1):5658.

Kuderna LFK, Ulirsch JC, Rashid S, Ameen M, Sundaram L, Hickey G, et al.. Identification of constrained sequence elements across 239 primate genomes. Nature. 2024;625(7996):735-742.

Wang Q, Clark KM, Tiwari R, Raju N, Tharp GK, Rogers J, et al.. The CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression. Cell. 2024;187(5):1223-1237.e16.

Watson A, Harris RA, Engevik AC, Oezguen N, Nicholson MR, Dooley S, et al.. MYO5B and the Polygenic Landscape of Very Early-Onset Inflammatory Bowel Disease in an Ethnically Diverse Population. Inflamm Bowel Dis. 2024;.

Patel H, Harris RA, Qian JH, Oezguen N, Watson A, Szigeti RG, et al.. Genetic Variation Between Small Bowel and Colon-Predominant Crohn's Disease. Cell Mol Gastroenterol Hepatol. 2024;17(6):1069-1071.

2023
Harris RA, Bush AH, Eagar TN, Qian J, Greenwood MP, Opekun AR, et al.. Exome Sequencing Implicates DGKZ , ESRRA , and GXYLT1 for Modulating Granuloma Formation in Crohn Disease. J Pediatr Gastroenterol Nutr. 2023;77(3):354-357.

Gao H, Hamp T, Ede J, Schraiber JG, McRae J, Singer-Berk M, et al.. The landscape of tolerated genetic variation in humans and primates. bioRxiv. 2023;.

Harris RA, McAllister JM, Strauss JF. Single-Cell RNA-Seq Identifies Pathways and Genes Contributing to the Hyperandrogenemia Associated with Polycystic Ovary Syndrome. Int J Mol Sci. 2023;24(13).

Kuderna LFK, Gao H, Janiak MC, Kuhlwilm M, Orkin JD, Bataillon T, et al.. A global catalog of whole-genome diversity from 233 primate species. Science. 2023;380(6648):906-913.

Gao H, Hamp T, Ede J, Schraiber JG, McRae J, Singer-Berk M, et al.. The landscape of tolerated genetic variation in humans and primates. Science. 2023;380(6648):eabn8153.

Sørensen EF, Harris RA, Zhang L, Raveendran M, Kuderna LFK, Walker JA, et al.. Genome-wide coancestry reveals details of ancient and recent male-driven reticulation in baboons. Science. 2023;380(6648):eabn8153.

Paulin LF, Raveendran M, Harris RA, Rogers J, von Haeseler A, Sedlazeck FJ. SVhound: detection of regions that harbor yet undetected structural variation. BMC Bioinformatics. 2023;24(1):23.

Harris RA, Archer KJ, Goodarzi MO, York TP, Rogers J, Dunaif A, et al.. Loci on chromosome 12q13.2 encompassing ERBB3, PA2G4 and RAB5B are associated with polycystic ovary syndrome. Gene. 2023;852:147062.

Harris RA, Raveendran M, Warren W, LaDeana HW, Tomlinson C, Graves-Lindsay T, et al.. Whole Genome Analysis of SNV and Indel Polymorphism in Common Marmosets (). Genes (Basel). 2023;14(12).

2022
Wang RJ, Peña-Garcia Y, Bibby MG, Raveendran M, Harris RA, Jansen HT, et al.. Examining the Effects of Hibernation on Germline Mutation Rates in Grizzly Bears. Genome Biol Evol. 2022;14(10).

Harris RA, Raveendran M, Lyfoung DT, Sedlazeck FJ, Mahmoud M, Prall TM, et al.. Construction of a new chromosome-scale, long-read reference genome assembly for the Syrian hamster, Mesocricetus auratus. Gigascience. 2022;11.

Gunter C, Harris RA, Kovacs-Balint Z, Raveendran M, Michopoulos V, Bachevalier J, et al.. Heritability of social behavioral phenotypes and preliminary associations with autism spectrum disorder risk genes in rhesus macaques: A whole exome sequencing study. Autism Res. 2022;15(3):447-463.

Wang RJ, Raveendran M, Harris RA, Murphy WJ, Lyons LA, Rogers J, et al.. De novo Mutations in Domestic Cat are Consistent with an Effect of Reproductive Longevity on Both the Rate and Spectrum of Mutations. Mol Biol Evol. 2022;39(7).

Lermi NOzirmak, Gray SB, Bowen CM, Reyes-Uribe L, Dray BK, Deng N, et al.. Comparative molecular genomic analyses of a spontaneous rhesus macaque model of mismatch repair-deficient colorectal cancer. PLoS Genet. 2022;18(4):e1010163.